SURGICAL DISEASES, TRAUMATOLOGY, ORTHOPEDICS, UROLOGY : OCTET FIBROUS (OSTITIS FIBROSA) - etiology, pathogenesis, symptoms and course of, recognition, prediction and prevention
Etiology and pathogenesis is not completely clarified; they are, apparently, different local and generalized form fibrous Ostia. When the local form of the process is limited to degenerative changes in bone and substance for a limited area. Changes can occur as a result of injury, improper loading of bones and other things, leading to malnutrition, bone degeneration and degenerative changes in the bone substance. Affects mostly long bones of the limbs, ribs, jaw; in the long tubular bones appear limited or solid fusiform thickening with the formation of cystic cavities of various sizes. The periosteum of these changes does not participate. In generalized form of dystrophic changes relate to the entire skeletal system; disruption of the normal state of the bone substance is put in the abnormal dependence on power, changes in the nervous system, lesions of the endocrine glands (abnormal function of the parathyroid glands). Affects the bones of the skull, pelvis, spine and long bones.
Symptoms. Uniform thickening of the bone, a small pain. Most often the process is detected during x-ray examinations of the fracture caused by minor trauma (pathological fracture).
For. The local form is localized normally in metafizik long bones, often in their diateza occurs in the form of local cystic fibrosis osteodystrophies. When x-ray study are defined thickened section of bone with a thin cortical layer, in the center one - or multi cysts; periosteal changes are absent. The character of the local fibrous osteodystrophies is the possibility of moving to the sarcoma. In generalized form is affected more bones; the process progresses slowly, causing the patient to a significant depletion and death. The soft tissue in the process are not involved.
Recognition of late due to the lack of early symptoms. Confirmed by characteristic x-ray. Should exclude sarcoma, chondroma, tuberculosis and Echinococcus bones.
When local fibrous osteodystrophies a favorable outcome. Fractures in the area of the cyst, usually comes self-treatment.
Of surgical interventions applied scraping the cavity of the cyst. In generalized form, the prognosis is poor. Due to unclear etiology treatment is symptomatic, radiotherapy is applied. As a General event, it is recommended the removal of the parathyroid glands.