FIBROSA HYPERPARATHYROID (OSTEODYSTROPHIA HYPERPARATHYREOTICA) DISEASE (RECKLINGHAUSEN)

FIBROSA HYPERPARATHYROID (OSTEODYSTROPHIA HYPERPARATHYREOTICA) DISEASE (RECKLINGHAUSEN)- QR

DISEASE OF THE ENDOCRINE GLANDS : - etiology, pathogenesis, symptoms and course of, recognition, prediction and prevention

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What is the FIBROSA HYPERPARATHYROID (OSTEODYSTROPHIA HYPERPARATHYREOTICA) DISEASE (RECKLINGHAUSEN) and how it is treated?

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Etiology and pathogenesis FIBROSA HYPERPARATHYROID (OSTEODYSTROPHIA HYPERPARATHYREOTICA) DISEASE (RECKLINGHAUSEN)

Disease of bones on the ground of an overactive parathyroid glands (hyperplasia, adenoma). Characterized by a negative balance of calcium metabolism, depletion of bone salts of calcium and the emergence of bone cystic formations. At the same time calcium salt can excess amount is deposited in organs and tissues, particularly in the kidneys, leading to the formation of concretions. Women get sick more often than men. The most frequent person of middle and old age.

 

Symptoms and course FIBROSA HYPERPARATHYROID (OSTEODYSTROPHIA HYPERPARATHYREOTICA) DISEASE (RECKLINGHAUSEN)

Symptoms. Bone pain, aggravated by movement, progressive fatigue and weakness, weight loss. Multiple deformation, fractures of the bones. The characteristic sound of a ripe watermelon with percussion of the skull due to the formation of cavities in the bone tissue. Often there is kyphosis and scoliosis, deformity of the pelvic bones, bones, both flat and tubular, can produmyvatsya tumor size from a pea to the head of the newborn. X-rays of the bones indicate osteoporosis, tumors and cystic cavities in the bones, thinning and even the disappearance of bone tissue. There is often persistent anorexia, vomiting, persistent constipation, polyuria, hypercalciuria and hyperphosphaturia, albuminuria, renal colic with the formation of urinary stones or sand. Calcium levels and blood increased (up to 15 mg% instead of the normal 9 - 11 mg%), the phosphorus level in the blood is low (below 2.5 mg%), the content phosphatase increased (up to 0.6 mg% instead of the normal 0.1 - 0.2 mg%). In some cases there is a violation of the water balance and the form of diabetes insipidus. In rare cases it is possible to palpate a tumor of the parathyroid gland.

For in most cases slow.

Recognition FIBROSA HYPERPARATHYROID (OSTEODYSTROPHIA HYPERPARATHYREOTICA) DISEASE (RECKLINGHAUSEN)

The high content of calcium in the blood is a characteristic that distinguishes the disease from other bone diseases not associated with lesions of the parathyroid glands.

 

Predictions FIBROSA HYPERPARATHYROID (OSTEODYSTROPHIA HYPERPARATHYREOTICA) DISEASE (RECKLINGHAUSEN)

Prediction in non-running cases, when possible, surgical treatment is relatively favorable. In severe, advanced cases even the removal of a tumor of the parathyroid gland does not give the full effect. Death may occur due to high hypercalcemia (greater than 15 mg%) or dysfunction of vital organs (kidneys).

 

Treatment.

The operation of removal of a tumor of the parathyroid gland or partial resection of hyperplastic parathyroid glands. The use of local therapy for cystic cavities in the bones may provide temporary improvement in the areas exposed to radiation.

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