DISEASES OF THE BLOOD SYSTEM : MYELOMA MULTIPLE. DISEASE RUSTICOLA - etiology, pathogenesis, symptoms and course of, recognition, prediction and prevention
The etiology is unknown.
The pathogenesis. Multiple myeloma true tumor (hemoblastosis), the starting point are reticular cells in the bone marrow various parts of the skeleton.
Symptoms. Marked tenderness of the bones when pressed on them. Often patients experience acute pain in the long bones of the skeleton, which can be mistaken for rheumatism. Along with pain, there is often persistent fever, which in a few months, and sometimes up to the death of patients does not abate. From the peripheral blood usually special deviations from the norm to mention fails, but sometimes blood picture has a typical leukemia character (type Milosa); leukocytosis with simultaneous appearance in the peripheral blood of myeloblasts, myelocytes and erythroblasts.
Course and complications. The disease is chronic, sometimes acute. The consequence of the presence of tumors in the bones is extraordinary fragility. Multiple fractures observed in patients, make them disabled. The disease is often complicated by bedsores, pneumonia, septicopyemia typical leukemia and other
The recognition. Characterized by excretion in the urine albuminous body Bains-Jones. Radiographically characterized by a round of enlightenment in the affected process the bones, especially the skull and pelvis.
Deep x-ray treatments of the bones in the areas of localization of tumors, symptomatic: heart (camphor, caffeine, digitalis), pain - morphine, pantopon. A light buffet. In the presence of anemia should try a blood transfusion (200 ml).